| Sample Size calculation in Clinical Research | TrialSize-package TrialSize |
| A + B Escalation Design with Dose De-escalation | AB.withDescalation |
| A + B Escalation Design without Dose De-escalation | AB.withoutDescalation |
| Average Bioequivalence | ABE |
| ANOVA with Repeat Measures | ANOVA.Repeat.Measure |
| Test the Carry-over effect | Carry.Over |
| Cochran-Armitage's Test for Trend | Cochran.Armitage.Trend |
| Test for equality in Cox PH model. | Cox.Equality |
| Test for Equivalence in Cox PH model. | Cox.Equivalence |
| Test for non-inferiority/superiority in Cox PH model. | Cox.NIS |
| Test for Equality of Intra-Subject Variabilities in Crossover Design | CrossOver.ISV.Equality |
| Test for Similarity of Intra-Subject Variabilities in Crossover Design | CrossOver.ISV.Equivalence |
| Test for Non-Inferiority/Superiority of Intra-Subject Variabilitie in Crossover Design | CrossOver.ISV.NIS |
| Williams' Test for Minimum effective dose (MED) | Dose.Min.Effect |
| Linear Contrast Test for Binary Dose Response Study | Dose.Response.binary |
| Linear Contrast Test for Dose Response Study | Dose.Response.Linear |
| Linear Contrast Test for Time-to-Event Endpoint in dose response study | Dose.Response.time.to.event |
| Test Goodness of Fit by Pearson's Test | gof.Pearson |
| Test Goodness of Fit by Pearson's Test for two-way table | gof.Pearson.twoway |
| Individual Bioequivalence | IBE |
| Test for Equality of Inter-Subject Variabilities | InterSV.Equality |
| Test for Equality of Inter-Subject Variabilities | InterSV.NIS |
| Test for Equality of Intra-Subject CVs | ISCV.Equality |
| Test for Equivalence of Intra-Subject CVs | ISCV.Equivalence |
| Test for Non-Inferiority/Superiority of Intra-Subject CVs | ISCV.NIS |
| Test for Equality of Intra-Subject Variabilities | ISV.Equality |
| Test for Similarity of Intra-Subject Variabilities | ISV.Equivalence |
| Test for Non-Inferiority/Superiority of Intra-Subject Variabilities | ISV.NIS |
| McNemar Test in 2 by 2 table | McNemar.Test |
| Test for Equality in Multiple-Sample William Design | MeanWilliamsDesign.Equality |
| Test for Equivalence in Multiple-Sample William Design | MeanWilliamsDesign.Equivalence |
| Test for Non-Inferiority/Superiority in Multiple-Sample William Design | MeanWilliamsDesign.NIS |
| Multiple Testing procedures | Multiple.Testing |
| Test for independence for nonparametric study | Nonpara.Independ |
| One Sample Location problem in Nonparametric | Nonpara.One.Sample |
| Two sample location problem for Nonparametric | Nonpara.Two.Sample |
| One Sample Mean Test for Equality | OneSampleMean.Equality |
| One Sample Mean Test for Equivalence | OneSampleMean.Equivalence |
| One Sample Mean Test for Non-Inferiority/Superiority | OneSampleMean.NIS |
| One sample proportion test for equality | OneSampleProportion.Equality |
| One sample proportion test for equivalence | OneSampleProportion.Equivalence |
| One sample proportion test for Non-inferiority/Superiority | OneSampleProportion.NIS |
| One-Sided Tests with fixed effect sizes | OneSide.fixEffect |
| One-Sided Tests with varying effect sizes | OneSide.varyEffect |
| Pairwise Comparison for Multiple-Sample One-Way ANOVA | OneWayANOVA.pairwise |
| One-way ANOVA pairwise comparison | OneWayANOVA.PairwiseComparison |
| Population Bioequivalence | PBE |
| Propensity Score ignoring strata | Propensity.Score.nostrata |
| Propensity Score with Stratas | Propensity.Score.strata |
| Quality of life | QOL |
| Crossover Design in QT/QTc Studies without covariates | QT.crossover |
| Parallel Group Design in QT/QTc Studies without covariates | QT.parallel |
| Crossover Design in QT/QTc Studies with PK response as covariate | QT.PK.crossover |
| Parallel Group Design in QT/QTc Studies with PK response as covariate | QT.PK.parallel |
| Relative Risk in Parallel Design test for Equality | RelativeRisk.Equality |
| Relative Risk in Parallel Design test for Equivalence | RelativeRisk.Equivalence |
| Relative Risk in Parallel Design test for Non-inferiority/Superiority | RelativeRisk.NIS |
| Relative Risk in Crossover Design test for Equality | RelativeRiskCrossOver.Equality |
| Relative Risk in Crossover Design test for Equivalence | RelativeRiskCrossOver.Equivalence |
| Relative Risk in Crossover Design test for Non-inferiority/Superiority | RelativeRiskCrossOver.NIS |
| Calculate the power for Sensitivity Index | Sensitivity.Index |
| Stuart-Maxwell Test | Stuart.Maxwell.Test |
| Two Sample Crossover Design Test for Equality | TwoSampleCrossOver.Equality |
| Two Sample Crossover Design Test for Equivalence | TwoSampleCrossOver.Equivalence |
| Two Sample Crossover Design Test for Non-Inferiority/Superiority | TwoSampleCrossOver.NIS |
| Two Sample Mean Test for Equality | TwoSampleMean.Equality |
| Two Sample Mean Test for Equivalence | TwoSampleMean.Equivalence |
| Two Sample Mean Test for Non-Inferiority/Superiority | TwoSampleMean.NIS |
| Two sample proportion test for equality | TwoSampleProportion.Equality |
| Two sample proportion test for equivalence | TwoSampleProportion.Equivalence |
| Two sample proportion test for Non-Inferiority/Superiority | TwoSampleProportion.NIS |
| Two sample proportion Crossover design test for equality | TwoSampleSeqCrossOver.Equality |
| Two sample proportion Crossover design test for equivalence | TwoSampleSeqCrossOver.Equivalence |
| Two sample proportion Crossover design for Non-inferiority/Superiority | TwoSampleSeqCrossOver.NIS |
| Test for two sample conditional data in exponential model for survival data | TwoSampleSurvival.Conditional |
| Test for two sample equality in exponential model for survival data | TwoSampleSurvival.Equality |
| Test for two sample equivalence in exponential model for survival data | TwoSampleSurvival.Equivalence |
| Test for two sample Non-Inferiority/Superiority in exponential model for survival data | TwoSampleSurvival.NIS |
| Two-Sided Tests with fixed effect sizes | TwoSide.fixEffect |
| Two-Sided Tests with varying effect sizes | TwoSide.varyEffect |
| Composite Efficacy Measure(CEM) for Vaccine clinical trials. | Vaccine.CEM |
| The evaluation of vaccine efficacy with Extremely Low Disease Incidence(ELDI) | Vaccine.ELDI |
| Reduction in Disease Incidence(RDI) for Vaccine clinical trials. | Vaccine.RDI |
| In Vitro Bioequivalence | Vitro.BE |
| William Design test for equality | WilliamsDesign.Equality |
| Williams Design test for equivalence | WilliamsDesign.Equivalence |
| Williams Design test for Non-inferiority/Superiority | WilliamsDesign.NIS |
