Package: TrialSize 1.4.1

Vicky Qian Wu

TrialSize: R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research

Functions and Examples in Sample Size Calculation in Clinical Research.

Authors:Ed Zhang ; Vicky Qian Wu ; Shein-Chung Chow ; Harry G.Zhang <[email protected]>

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TrialSize/json (API)

# Install 'TrialSize' in R:
install.packages('TrialSize', repos = c('https://wuqian77.r-universe.dev', 'https://cloud.r-project.org'))
Uses libs:
  • c++– GNU Standard C++ Library v3

On CRAN:

Conda:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

cpp

3.95 score 4 stars 1 packages 106 scripts 1.0k downloads 7 mentions 85 exports 0 dependencies

Last updated from:7c118a2124. Checks:13 OK. Indexed: yes.

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Exports:AB.withDescalationAB.withoutDescalationABEANOVA.Repeat.MeasureCarry.OverCochran.Armitage.TrendCox.EqualityCox.EquivalenceCox.NISCrossOver.ISV.EqualityCrossOver.ISV.EquivalenceCrossOver.ISV.NISDose.Min.EffectDose.Response.binaryDose.Response.LinearDose.Response.time.to.eventgof.Pearsongof.Pearson.twowayIBEInterSV.EqualityInterSV.NISISCV.EqualityISCV.EquivalenceISCV.NISISV.EqualityISV.EquivalenceISV.NISMcNemar.TestMeanWilliamsDesign.EqualityMeanWilliamsDesign.EquivalenceMeanWilliamsDesign.NISMultiple.TestingNonpara.IndependNonpara.One.SampleNonpara.Two.SampleOneSampleMean.EqualityOneSampleMean.EquivalenceOneSampleMean.NISOneSampleProportion.EqualityOneSampleProportion.EquivalenceOneSampleProportion.NISOneSide.fixEffectOneSide.varyEffectOneWayANOVA.pairwiseOneWayANOVA.PairwiseComparisonPBEPropensity.Score.nostrataPropensity.Score.strataQOLQT.crossoverQT.parallelQT.PK.crossoverQT.PK.parallelRelativeRisk.EqualityRelativeRisk.EquivalenceRelativeRisk.NISRelativeRiskCrossOver.EqualityRelativeRiskCrossOver.EquivalenceRelativeRiskCrossOver.NISSensitivity.IndexStuart.Maxwell.TestTwoSampleCrossOver.EqualityTwoSampleCrossOver.EquivalenceTwoSampleCrossOver.NISTwoSampleMean.EqualityTwoSampleMean.EquivalenceTwoSampleMean.NISTwoSampleProportion.EqualityTwoSampleProportion.EquivalenceTwoSampleProportion.NISTwoSampleSeqCrossOver.EqualityTwoSampleSeqCrossOver.EquivalenceTwoSampleSeqCrossOver.NISTwoSampleSurvival.EqualityTwoSampleSurvival.EquivalenceTwoSampleSurvival.NISTwoSide.fixEffectTwoSide.varyEffectVaccine.CEMVaccine.ELDIVaccine.RDIVitro.BEWilliamsDesign.EqualityWilliamsDesign.EquivalenceWilliamsDesign.NIS

Dependencies:

Readme and manuals

Help Manual

Help pageTopics
Sample Size calculation in Clinical ResearchTrialSize-package TrialSize
A + B Escalation Design with Dose De-escalationAB.withDescalation
A + B Escalation Design without Dose De-escalationAB.withoutDescalation
Average BioequivalenceABE
ANOVA with Repeat MeasuresANOVA.Repeat.Measure
Test the Carry-over effectCarry.Over
Cochran-Armitage's Test for TrendCochran.Armitage.Trend
Test for equality in Cox PH model.Cox.Equality
Test for Equivalence in Cox PH model.Cox.Equivalence
Test for non-inferiority/superiority in Cox PH model.Cox.NIS
Test for Equality of Intra-Subject Variabilities in Crossover DesignCrossOver.ISV.Equality
Test for Similarity of Intra-Subject Variabilities in Crossover DesignCrossOver.ISV.Equivalence
Test for Non-Inferiority/Superiority of Intra-Subject Variabilitie in Crossover DesignCrossOver.ISV.NIS
Williams' Test for Minimum effective dose (MED)Dose.Min.Effect
Linear Contrast Test for Binary Dose Response StudyDose.Response.binary
Linear Contrast Test for Dose Response StudyDose.Response.Linear
Linear Contrast Test for Time-to-Event Endpoint in dose response studyDose.Response.time.to.event
Test Goodness of Fit by Pearson's Testgof.Pearson
Test Goodness of Fit by Pearson's Test for two-way tablegof.Pearson.twoway
Individual BioequivalenceIBE
Test for Equality of Inter-Subject VariabilitiesInterSV.Equality
Test for Equality of Inter-Subject VariabilitiesInterSV.NIS
Test for Equality of Intra-Subject CVsISCV.Equality
Test for Equivalence of Intra-Subject CVsISCV.Equivalence
Test for Non-Inferiority/Superiority of Intra-Subject CVsISCV.NIS
Test for Equality of Intra-Subject VariabilitiesISV.Equality
Test for Similarity of Intra-Subject VariabilitiesISV.Equivalence
Test for Non-Inferiority/Superiority of Intra-Subject VariabilitiesISV.NIS
McNemar Test in 2 by 2 tableMcNemar.Test
Test for Equality in Multiple-Sample William DesignMeanWilliamsDesign.Equality
Test for Equivalence in Multiple-Sample William DesignMeanWilliamsDesign.Equivalence
Test for Non-Inferiority/Superiority in Multiple-Sample William DesignMeanWilliamsDesign.NIS
Multiple Testing proceduresMultiple.Testing
Test for independence for nonparametric studyNonpara.Independ
One Sample Location problem in NonparametricNonpara.One.Sample
Two sample location problem for NonparametricNonpara.Two.Sample
One Sample Mean Test for EqualityOneSampleMean.Equality
One Sample Mean Test for EquivalenceOneSampleMean.Equivalence
One Sample Mean Test for Non-Inferiority/SuperiorityOneSampleMean.NIS
One sample proportion test for equalityOneSampleProportion.Equality
One sample proportion test for equivalenceOneSampleProportion.Equivalence
One sample proportion test for Non-inferiority/SuperiorityOneSampleProportion.NIS
One-Sided Tests with fixed effect sizesOneSide.fixEffect
One-Sided Tests with varying effect sizesOneSide.varyEffect
Pairwise Comparison for Multiple-Sample One-Way ANOVAOneWayANOVA.pairwise
One-way ANOVA pairwise comparisonOneWayANOVA.PairwiseComparison
Population BioequivalencePBE
Propensity Score ignoring strataPropensity.Score.nostrata
Propensity Score with StratasPropensity.Score.strata
Quality of lifeQOL
Crossover Design in QT/QTc Studies without covariatesQT.crossover
Parallel Group Design in QT/QTc Studies without covariatesQT.parallel
Crossover Design in QT/QTc Studies with PK response as covariateQT.PK.crossover
Parallel Group Design in QT/QTc Studies with PK response as covariateQT.PK.parallel
Relative Risk in Parallel Design test for EqualityRelativeRisk.Equality
Relative Risk in Parallel Design test for EquivalenceRelativeRisk.Equivalence
Relative Risk in Parallel Design test for Non-inferiority/SuperiorityRelativeRisk.NIS
Relative Risk in Crossover Design test for EqualityRelativeRiskCrossOver.Equality
Relative Risk in Crossover Design test for EquivalenceRelativeRiskCrossOver.Equivalence
Relative Risk in Crossover Design test for Non-inferiority/SuperiorityRelativeRiskCrossOver.NIS
Calculate the power for Sensitivity IndexSensitivity.Index
Stuart-Maxwell TestStuart.Maxwell.Test
Two Sample Crossover Design Test for EqualityTwoSampleCrossOver.Equality
Two Sample Crossover Design Test for EquivalenceTwoSampleCrossOver.Equivalence
Two Sample Crossover Design Test for Non-Inferiority/SuperiorityTwoSampleCrossOver.NIS
Two Sample Mean Test for EqualityTwoSampleMean.Equality
Two Sample Mean Test for EquivalenceTwoSampleMean.Equivalence
Two Sample Mean Test for Non-Inferiority/SuperiorityTwoSampleMean.NIS
Two sample proportion test for equalityTwoSampleProportion.Equality
Two sample proportion test for equivalenceTwoSampleProportion.Equivalence
Two sample proportion test for Non-Inferiority/SuperiorityTwoSampleProportion.NIS
Two sample proportion Crossover design test for equalityTwoSampleSeqCrossOver.Equality
Two sample proportion Crossover design test for equivalenceTwoSampleSeqCrossOver.Equivalence
Two sample proportion Crossover design for Non-inferiority/SuperiorityTwoSampleSeqCrossOver.NIS
Test for two sample conditional data in exponential model for survival dataTwoSampleSurvival.Conditional
Test for two sample equality in exponential model for survival dataTwoSampleSurvival.Equality
Test for two sample equivalence in exponential model for survival dataTwoSampleSurvival.Equivalence
Test for two sample Non-Inferiority/Superiority in exponential model for survival dataTwoSampleSurvival.NIS
Two-Sided Tests with fixed effect sizesTwoSide.fixEffect
Two-Sided Tests with varying effect sizesTwoSide.varyEffect
Composite Efficacy Measure(CEM) for Vaccine clinical trials.Vaccine.CEM
The evaluation of vaccine efficacy with Extremely Low Disease Incidence(ELDI)Vaccine.ELDI
Reduction in Disease Incidence(RDI) for Vaccine clinical trials.Vaccine.RDI
In Vitro BioequivalenceVitro.BE
William Design test for equalityWilliamsDesign.Equality
Williams Design test for equivalenceWilliamsDesign.Equivalence
Williams Design test for Non-inferiority/SuperiorityWilliamsDesign.NIS